ABSTRACT
An eight-year-old male child presenting with history of generalized convulsions, gradual loss of speech and generalized EEG (electroencephalography) abnormalities was diagnosed as Landau Kleffner Syndrome. He initially developed generalized convulsions which later changed to partial seizures during the course of illness. He was started on sodium valproate and continued with the drug (30 mg/kg/day) on which, he showed improvement in speech, behavior, hyperkinesis and frequency of convulsions during the follow-up.
Subject(s)
Child , Diagnosis, Differential , Electroencephalography , Humans , Landau-Kleffner Syndrome/diagnosis , Male , Valproic Acid/therapeutic useABSTRACT
This paper explores the relationships between maternal weight, height and poor pregnancy outcome using a data set from a case-control study of low birth weight (LBW) and perinatal mortality in Ahmedabad, India. Maternal height and weights were compared between mothers of 611 perinatal deaths, 644 preterm-LBW, and 1465 normal birth weight controls as well as 617 small-for-gestational age (SGA) and 1851 appropriate-for-gestational-age (AGA) births. Weight and height were much lower in this population compared to western standards. Low weight and height were associated with increased risk of perinatal death, prematurity and SGA. After adjusting for confounders, maternal weight remained significantly associated with poor pregnancy outcomes, whereas height was only weakly associated. Attributable risk estimates show that low weight is a much more important contributor to poor outcome than low height. Improvement in maternal nutritional status could lead to substantial improvement in birth outcome in this population.
Subject(s)
Birth Weight , Body Height , Body Weight , Case-Control Studies , Female , Humans , India/epidemiology , Infant Mortality , Infant, Low Birth Weight , Infant, Newborn , Infant, Premature , Infant, Small for Gestational Age , Nutritional Status , Pregnancy , Pregnancy Outcome , Risk FactorsABSTRACT
A review of postabortal sepsis following a 2-year study undertaken at the Department of Obstetrics and Gynaecology, SSG Hospital, Baroda is presented here with a view to know the incidence of postabortal sepsis and septic induced abortions and to re-evaluate the effectiveness of the MTP services in reducing its impact on maternal morbidity and mortality, since the implementation of the MTP Act in 1972. It has been observed that postabortal sepsis is a major cause of maternal mortality even now and MCH service is to be improved to reduce the same.
Subject(s)
Abortion, Criminal , Abortion, Septic/complications , Abortion, Spontaneous/complications , Female , Humans , Infections/etiology , PregnancyABSTRACT
A case of paraganglioma of the cauda equina is presented. Usually reported to be benign with good prognosis, the present patient had a somewhat different course. The behaviour of the tumour was unusual, with rapid recurrence seen within first month of surgery. The need for total surgical excision and role of adjuvant radiotherapy is highlighted.
Subject(s)
Cauda Equina , Combined Modality Therapy , Female , Humans , Middle Aged , Paraganglioma/therapy , Peripheral Nervous System Neoplasms/therapySubject(s)
Adult , Female , Humans , India , Infant, Low Birth Weight , Infant, Newborn , Male , PregnancyABSTRACT
Benzamido (alkyl) methyl pyrrolidine Mannich bases were synthetized and subjected to certain neuropharmacological studies. All the bases reduced the pentobarbitone sleeping time and rota-rod grip of rats. The Mannich bases II, III and V raised the minimal electro-shock seizure threshold of rats. The TAB-induced pyrexia was not reduced by the bases I and III in rabbits. None of the bases showed any significant analgesic activity.
Subject(s)
Amines/pharmacology , Animals , Body Temperature/drug effects , Brain/drug effects , Male , Mannich Bases/pharmacology , Pentobarbital/pharmacology , Postural Balance/drug effects , Rabbits , Rats , Receptors, Drug/metabolism , Sensory Thresholds/drug effects , Sleep/drug effects , Time FactorsSubject(s)
Adolescent , Adult , Age Factors , Aged , Animals , Bites and Stings/complications , Child , Child, Preschool , Dogs/physiology , Extremities , Female , Humans , Immunization/methods , India , Male , Middle Aged , Patient Compliance , Rabies/drug therapy , Rabies Vaccines/therapeutic use , Seasons , Sex FactorsSubject(s)
Adolescent , Adult , Body Height , Body Weight , Female , Humans , India , Male , Students , UniversitiesABSTRACT
Intraventricular injection of histamine and normal saline in rats caused a marked fall in adrenal ascorbic acid indicating a stimulatory effect of both on pituitary adrenal axis. Intraventricularly injected histamine caused significant hypoglycaemia also in rats as compared to control series.